Imagerie et stratégies thérapeutiques pour les cancers et tissus cérébraux

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Une thérapie matricielle pour optimiser la thérapie basée sur les vésicules extracellulaires dérivées de MSC pour protéger et réparer le cerveau ischémié · 2021
• Recherche et developpement pour la production de radioéléments innovants · 2019

Publications HAL récentes repérées

• Specific alterations of reactive species interactome markers reflect recovery after mild traumatic brain injury · 2026

  Résumé de la publication : Recovery from mild traumatic brain injury (mTBI) is believed to be mediated by the secondary injury response with oxidative stress (OS) playing a central role. Previous studies have largely examined isolated OS markers, yielding inconsistent results. This study adopts a more integrated…

• Combining Aggregate Data and Individual Patient Data in Model‐Based Meta‐Analysis: An Illustrative Case Study of Tofacitinib in Rheumatoid Arthritis Patients · 2026

  Résumé de la publication : Model-based meta-analysis (MBMA) utilizes aggregate data (AD) and allows integration of information from multiple studies, which may provide more statistical power to detect clinically relevant treatment effects than an individual randomized controlled trial alone. Access to individual patient data (IPD) is often…

• Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging · 2026

  Résumé de la publication : The geroscience hypothesis suggests that understanding mechanisms underlying aging will enable us to delay and lessen agerelated disability and diseases. The role of mechanical factors has been increasingly appreciated in many aspects of the aging process. Here, we use mouse models to…

• Low-dose ionizing radiation, a protective intervention to mitigate chronic cerebral hypoperfusioninduced brain damage and cognitive deficits in the rat Running · 2026

  Résumé de la publication : Vascular dementia is a leading cause of cognitive decline with few effective treatment options currently available. In the framework of hormesis, low-doses of ionizing radiation (LDIR<0.1 Gy) has been advanced as a promising therapy for neurodegenerative diseases. This study investigates the actions…

• Hematological immune-related adverse events associated with checkpoint inhibitors · 2026

  Résumé de la publication : Background: The use of immune checkpoint inhibitors (ICIs) has expanded substantially across tumor types, establishing them as a cornerstone of modern oncology. However, the frequency and severity of immune-related adverse events (irAEs) remain underestimated, particularly hematologic toxicities, which can be life-threatening and…