RESTORE, a geroscience and rejuvenation research center

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Prédire la santé musculaire grâce à la dynamique des cellules stromales adipeuses et du fascia · 2026
• Une plateforme robotisée AFM et IA pour un contrôle qualité amélioré et une identification précoce de la différenciation des cellules souches mésenchymateuses · 2026
• Les morphométriques fonctionnels: Un nouveau paradigme pour explorer l'hétérogénéité mitochondriale · 2026

Publications HAL récentes repérées

• FALCON : An effective and robust method for active clustering with pairwise constraints · 2027

  Résumé de la publication : Constraint-based clustering incorporates user knowledge into the clustering process through pairwise constraints, which specify whether two elements should be linked (Must-Link) or separated (Cannot-Link). Active constraintbased clustering extends this framework by selecting constraints iteratively to improve clustering quality while minimizing user effort.…

• A personalized home-based exercise training program in children with Marfan and Loeys-Dietz syndromes improves aerobic exercise capacity and health-related quality of life · 2026

  Résumé de la publication : Background: Children and adolescents with Marfan (MFS) and Loeys-Dietz (LDS) syndromes report chronic fatigue and reduced physical endurance, which significantly impact their health-related quality of life (HRQoL). We hypothesized that a tailored physical training program could improve these parameters. To test this…

• Wrapshap a high dimension feature selection framework to explore biological systems through machine learning explanations · 2026

  Résumé de la publication : Among the existing feature selection (FS) methods in machine learning (ML), those known as wrapper methods often produce the most effective subset of features. However, their high computational cost and tendency to overfit make them impractical for high-dimensional data, as is frequently…

• Digitally scanned light-sheet Brillouin microscopy and force inference : a strategy toward quantitative tissue mechanics · 2026

  Résumé de la publication : This thesis describes the development and implementation of a novel, integrated microscopy platform for advanced research in tissue mechanics and extracellular matrix (ECM) remodeling. The platform integrates three key modalities: Brillouin microscopy, enabling non-contact and label-free measurement of tissue mechanical properties; light…

• International guideline on genetic testing of children with short stature · 2026

  Résumé de la publication : Abstract Short stature may be caused by a multitude of conditions, including genetic and non-genetic causes. Over the last decade, advances in genetic sequencing technologies have revolutionized our understanding of the underlying physiology of growth and greatly increased our ability to identify…