Unité Biologie des Spirochètes

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Publications HAL récentes repérées

• Leptospirosis Prevalence and Risk Factors Among Patients Presenting With Fever to 4 Healthcare Sites in Sub-Saharan Africa and South East Asia: An International Multisite Observational and Nested Case-Control Study · 2026

  Résumé de la publication : Background We investigated the prevalence, diversity, and risk factors for acute leptospirosis in the Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE) study. Methods Febrile patients aged ≥2 months in Laos, Malawi, Mozambique, and Zimbabwe underwent a standardized clinical and…

• DMEM and EMEM are suitable surrogate media to mimic host environment and expand leptospiral pathogenesis studies using in vitro tools · 2026

  Résumé de la publication : Pathogenic Leptospira species can survive and thrive in a wide range of environments. Distinct environments expose the bacteria to different temperatures, osmolarities, and amounts and sources of nutrition. However, leptospires are mostly cultured, in a laboratory setting under in vitro conditions that…

• In vitro and in vivo endothelial interactions of Leptospira species are markers of virulence · 2026

  Résumé de la publication : Leptospirosis is a global zoonotic disease caused by pathogenic species of the genus Leptospira . Leptospira species are classified into two major clades (pathogenic, P, and saprophytic, S), and four subclades (P1, P2, S1, and S2), with the P1 subclade further divided…

• Leptospirosis Incidence at Four Sites in Sub-Saharan Africa and South East Asia: An International Multi-Site Hybrid Surveillance Study · 2026

  Résumé de la publication : Background There are few leptospirosis incidence studies despite such estimates being central to accurate burden of disease estimation. We used data from the multicenter Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE) study to make leptospirosis incidence estimates from new…

• DMEM and EMEM as alternate growth media for pathogenic Leptospira · 2026

  Résumé de la publication : Pathogenic Leptospira species can survive and thrive in a wide range of environments. Distinct environments expose the bacteria to different temperatures, osmolarities, and amounts and sources of nutrition. However, leptospires are mostly cultured in a laboratory setting under in vitro conditions that…