Laboratoire de Bioimagerie et Pathologies (UMR 7021)

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Exploration du mécanisme de dépliement des acides nucléiques par la protéine Cellular Nucleic acid Binding Protein (CNBP) · 2026
• EV-GRAFT Une plateforme polyvalente pour suivre, explorer et manipuler les vésicules extracellulaires · 2024
• Rôle des lipides hôtes dans l'assemblage et l'entrée virale à l'échelle nanométrique · 2024

Publications HAL récentes repérées

• Plasma Membrane‐Promoted Aggregation of BODIPY Dimers Enables Live‐Cell Super‐Resolution Imaging · 2026

  Résumé de la publication : Molecular aggregation profoundly alters the optical properties of fluorophores, yet its behavior in dynamic biological environments remains insufficiently understood and rarely harnessed functionally. Here, we report a membrane-controlled aggregation strategy based on plasma membrane-targeted BODIPY dimers engineered to undergo tunable H -and…

• Exploring gefitinib to enhance endocytosis of antibodies and nucleic acid aptamers targeting EGFR in glioblastoma · 2026

  Résumé de la publication : Active targeting in drug delivery involves the binding of ligands to receptors present on the surface of targeted cells. Several conjugates are already in use or under development for active targeting of tumors, the most widely known being antibody-drug conjugates (ADC). They…

• Engineering stable wax-based w1/O/W2 double emulsions for high-payload encapsulation, osmotic resistance, and temperature-activated permeability · 2026

  Résumé de la publication : Water-in-oil-in-water (w 1 /O/W 2 ) double emulsions can compartmentalize hydrophilic actives at high aqueous loadings, but osmotic gradients and interfacial transport often drive premature leakage. This remains a key limitation for high-payload hydrophilic formulations exposed to dilution or osmotic shocks during…

• An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane · 2026

  Résumé de la publication : Exogenous phosphatidylserine (PS) is cytotoxic to Chinese hamster ovary (CHO) cells with a PS-resistant CHO cell mutant exhibiting impaired transbilayer movement of a fluorescent PS analog at the plasma membrane. Here, we demonstrate that both mRNA and protein levels of 14-3-3 zeta…

• Polymer Chemistry and the Kinetics of Nanoprecipitation · 2026

  Résumé de la publication : Loaded polymer nanoparticles (NPs) are a cornerstone of modern nanomedicine, underpinning applications that span biosensing, bioimaging, and therapy. A detailed understanding of the NP formation process is essential for reliable up-scaling and for engineering ever more sophisticated nanostructures. In this work, using…