Institut de Recherche en Infectiologie de Montpellier

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Efficacité des fluoroquinolones dans la nocardiose cérébrale : une approche intégrée · 2026
• Immunodéficience somatique chez les patients âgés atteints d'une maladie mycobactérienne · 2026
• Liaison de diverses particules extracellulaires aux cellules réceptrices : de la physiologie cutanée à la maladie et à l'infection virale · 2026

Publications HAL récentes repérées

• The Gene Encoding the Antisense Protein ASP of HIV-1: Origin, Distribution and Maintenance · 2026

  Résumé de la publication : Human Immunodeficiency Virus Type 1 (HIV-1), the causative agent of the acquired immune deficiency syndrome (AIDS), originated from zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting African great apes, following complex cross-species transmission events and virus–host co-evolution. These processes were accompanied by…

• Development of Isoniazid–Pyrazole Hybrids as Potential Antitubercular Agents · 2026

  Résumé de la publication : A series of INH–pyrazole molecular hybrids (6a–o) was synthesized and evaluated for in vitro anti-tubercular activity against drug-susceptible, multidrug-resistant (MDR), and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains, alongside their corresponding precursors (4a–o), using isoniazid (INH) as the reference drug. Overall, the hybrid…

• Smooth-to-rough morphotype switching, a mechanism of phage resistance in Mycobacterium abscessus · 2026

  Résumé de la publication : Mycobacterium abscessus infections represent a growing global health concern due to their severe pathology and difficulty of treatment, largely driven by their intrinsic antimicrobial resistance. While phage therapy has emerged as a promising alternative approach, studies have predominantly focused on glycopeptidolipids (GPL)-deficient…

• Zika virus reprograms the host tRNA epitranscriptome to adapt translation to A-ending codon bias · 2026

  Résumé de la publication : The codon usage bias of the Zika virus (ZIKV) genome is skewed towards AA-ending codons, which are preferentially decoded by U34-modified cognate tRNAs. This contrasts with the human host’s preference for AG-ending codons, suggesting that ZIKV may exploit specific tRNA modifications to…

• Single-cell characterization of skin response to a bite by West Nile virus-infected mosquito reveals fibroblast-mediated barrier to transmission · 2026

  Résumé de la publication : Cutaneous events determining transmission of mosquito-borne orthoflaviviruses remain largely uncharacterized. Here, we report single-cell RNA-sequencing of skin from immunocompetent mice exposed to West Nile virus-infected mosquitoes, capturing early response at a critical transmission bottleneck. Skin-resident fibroblasts, keratinocytes, and myeloid cells were exposed…