Microbiote et muqueuses pour la surveillance immunitaire du cancer

Domaines scientifiques déclarés au RNSR

Publications HAL récentes repérées

• Metabolic determinants of cancer immunotherapy outcomes identified by plasma profiling · 2026

  Résumé de la publication : Immune-checkpoint inhibitors benefit a subset of patients with advanced cancer, and the metabolic determinants of response remain unclear. Here, using targeted metabolomics and metagenomics, we profiled 4,336 plasma samples from 1,714 patients across five tumor types and 16 cohorts spanning Europe and…

• Neutralization of acyl-CoA-binding protein attenuates glucocorticoid-mediated suppression of cancer immunosurveillance · 2026

  Résumé de la publication : Glucocorticoids (GCs) are potent immunosuppressive agents that compromise anticancer immune responses, yet the molecular mediators of this effect remain incompletely understood. Here, we identify the acyl-CoA-binding protein/diazepam-binding inhibitor (ACBP/DBI) as a critical effector of the GC-induced suppression of tumor immunosurveillance and immunotherapy…

• Histidine-improved cancer immunosurveillance · 2026

  Résumé de la publication : No abstract available