LABORATOIRE DE GENETIQUE ET BIOLOGIE CELLULAIRE

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Etude des relations entre les transporteurs mitochondriaux de la famille Sidéroflexine, l'homéostasie du fer et la ferroptose · 2021
• Dérégulations induites par le facteur de susceptibilité majeur à la spondyloarthrite HLA-B27 : de la drosophile aux cellules de patients · 2019

Publications HAL récentes repérées

• Adenovirus phagocytosis by neutrophils triggers a pro-inflammatory response · 2026

  Résumé de la publication : Adenoviruses are common pathogens that have been engineered and used for medical purposes. While their recognition by innate immune cells such as macrophages and dendritic cells is well characterized, interactions with neutrophils remain poorly understood. Using cytometry,confocal and electron microscopy, we showed…

• Mating imperatives drive plasticity of the daily temporal niche in fruit flies · 2026

  Résumé de la publication : Animals confine their daily activity to distinct diurnal, crepuscular or nocturnal windows. It remains unclear how hundreds of sympatric species sharing the same temporal niche manage to coexist. To address this, we monitored the daily activity of the twilight-active, species-rich Drosophila genus…

• The Resistin/TLR4/miR-155-5p axis: a novel signaling pathway in the onset of hypothalamic neuroinflammation · 2025

  Résumé de la publication : Hypothalamic neuroinflammation plays a pivotal role in the development of metabolic disorders, contributing to obesity and insulin resistance. Hypercaloric diets rich, particularly high-fat diets (HFDs) induce hypothalamic neuroinflammation, which has been shown to precede peripheral inflammation, even after short-term exposure. However, the…

• ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context · 2025

  Résumé de la publication : Cystic fibrosis (CF) is a genetic disease caused by dysfunction in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) chloride channel. Patients with CF are hypersusceptible to Mycobacterium abscessus infection, a fast-growing mycobacterium and harmful opportunistic pathogen. Although CFTR dysfunction is known as…

• Visualization of Respiratory Syncytial Virus RNA Synthesis Sites by Ethynyl Uridine Labeling · 2025

  Résumé de la publication : Modified cell-permeable nucleosides such as 5-bromouridine 5′-triphosphate (BrUTP) or 5-ethynyluridine (5-EU), together with the powerful click chemistry, have been widely used to specifically label newly synthetized RNA in cells and tissues in a simple two-step approach. The use of cellular transcription inhibitors…