Centre de recherche sur l'inflammation

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• SGLT2, glycolyse et activation des cellules pariétales épithéliales · 2026
• Le canal calcique Orai1 : nouvelle cible thérapeutique dans l'hypertension pulmonaire · 2026
• L’axe acide rétinoïque–CARD9–cellules MAIT dans les interactions hôte-microbiote et la néphropathie à IgA · 2026

Publications HAL récentes repérées

• Machine Learning Models for Disease-Free Survival Analysis after Liver Resection for Hepatocellular Carcinoma: A Multicentric French Collaborative Study · 2026

  Résumé de la publication : Introduction: Liver resection (LR) is a potentially curative treatment of hepatocellular carcinoma (HCC), but early recurrence rates remain high reaching as high as 70%. Accurate prediction of disease-free survival (DFS) after LR is crucial to optimize patients’ selection for clinical trials evaluating…

• Adult male patients with DKC1 mutations present early-onset pulmonary fibrosis and severe prognosis · 2026

  Résumé de la publication : Background Mutations in telomere-related genes (TRGs) are the main cause of monogenic familial pulmonary fibrosis. Dyskerin, encoded by the X-localised gene DKC1 , is involved in telomere maintenance. Methods This retrospective study aimed to further characterise the pulmonary phenotype of DKC1 -deficient…

• Endoscopic ultrasound-guided pancreatic cavitation: Proof-of-Concept in a vascularized human cadaveric model · 2026

  Résumé de la publication : Background: Pancreatic ductal adenocarcinoma's poor prognosis is due in part to its desmoplastic tumor microenvironment (TME), which hinders the bioavailability of anti-tumor drugs. Selectively targeting the physical properties of TME by ultrasonic cavitation could make systemic therapies more effective. We have designed…

• Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers · 2026

  Résumé de la publication : Growing evidence underscores the importance of the first 1,000 days of life in shaping the gut-microbiome axis. This early-life window is critical in the establishment of long-term physiological trajectories and immunological adaptations, potentially influencing susceptibility to diseases linked to dysbiosis and barrier…

• Identification and validation of cilia-associated molecular candidates deregulated in severe asthma · 2026

  Résumé de la publication : Background: Asthma is characterised by a chronic inflammation and airway remodelling. The functionality of the asthma airway epithelium is altered, suggesting a central role in the pathophysiology. Cilia-associated abnormalities have been reported in the airway epithelium of asthmatic patients, but the mechanisms…