Microbiologie, Environnement Digestif et Santé

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Heritabilite de bovine d’un point de vue de holobiont · 2024
• DÉVELOPPEMENT DE NOUVELLES STRATÉGIES MÉDICAMENTEUSES POUR LA SCHISTOSOMIASE: DE LA FORME ORALE A L’ACTION ANTIHELMINTHIQUE · 2024
• LabCom — Microbiote intestinal et maladies métaboliques chez l’Homme : un système digestif in vitro unique pour catalyser le développement de stratégies nutritionnelles innovantes. · 2022

Publications HAL récentes repérées

• Critical quality attributes of glucomannans as tablet excipients: linking physicochemical properties to matrix performance and in vitro drug release · 2027

  Résumé de la publication : Glucomannans are natural polysaccharides increasingly investigated as pharmaceutical excipients due to their hydration, swelling, and rheological properties. However, variations in their structural features may strongly impact their performance in solid dosage forms. This study applies a Quality by Design (QbD) inspired comparative…

• Harnessing ecological niche modeling of Listeria monocytogenes for biopreservation system engineering · 2026

  Résumé de la publication : Biopreservation is a microbiome engineering technology based on the use of microorganisms as protective cultures and/or their metabolites, which can be used to mitigate the presence of pathogens in food. This study explores the potential of ecological niche modeling to guide the…

• Impact of yeast cell wall incorporation on the mucoadhesion, stability, oral permeability and release profile of alginate/whey protein beads loaded with insulin · 2026

  Résumé de la publication : This study aimed to evaluate the impact of incorporating yeast cell wall (YCW) into alginate/whey protein (ALG/WP) particles as a strategy to improve oral insulin delivery. Insulin-loaded particles were produced by an extrusion–gelation process with or without YCW, and their physicochemical, mucoadhesive,…

• Polysaccharides from Adansonia digitata combined with whey protein and alginate enhance the viscosity, swelling, controlled release, and mucoadhesion properties of hydrogels for oral drug delivery · 2026

  Résumé de la publication : The potential of Adansonia digitata (baobab) pulp polysaccharides (BB), combined with whey protein (WP) and alginate (ALG), was evaluated as a novel pharmaceutical excipient to enhance the viscosity, swelling behavior, controlled release, and mucoadhesive properties of hydrogels prepared by the ionotropic gelation…

• Lipid-based coating of supersaturated amorphous solid dispersions: could it represent an approach to improving their physical stability or oral bioavailability? · 2026

  Résumé de la publication : Amorphous solid dispersions (ASDs) are widely recognized as an effective formulation strategy to enhance the in vivo performance of poorly water-soluble drugs; however, their broader application is often limited by insufficient long-term physical stability especially if the drug load is higher than…