Unité Biologie et Pathogénicité Fongiques

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Publications HAL récentes repérées

• “Should I stay or should I go”—a kinase delays escape of Candida glabrata from macrophages · 2026

  Résumé de la publication : Candida glabrata is an opportunistic fungal pathogen that causes both superficial and systemic infections in humans, accounting for 15%–25% of invasive candidiasis cases. Macrophages play a crucial role in antifungal immunity by internalizing C. glabrata ; however, the fungus has evolved strategies…

• Exometabolome variation in the fungal pathogen of humans Candida albicans reveals specificities at the genetic clade and strain levels · 2026

  Résumé de la publication : Candida albicans is a fungal pathobiont that thrives in different host niches and successfully confronts the host immune defenses. The success of C. albicans as a pathogen relies on a highly plastic metabolism, with examples of variations across isolates; however, detailed characterization…

• Pediatric yeast fungaemia species patterns, resistance profiles, and outcomes: a 20-year surveillance study in Paris, France · 2026

  Résumé de la publication : Background The epidemiology of pediatric yeast bloodstream infections remains poorly characterized in high-income settings despite global shifts over the past two decades. As fungal species distribution varies geographically, national surveillance is essential. In France, recent reports have focused predominantly on adults, leaving…

• Candida albicans promotes TSST-1 production by Staphylococcus aureus through glucose depletion and relief of CcpA-mediated repression · 2026

  Résumé de la publication : Menstrual toxic shock syndrome (mTSS) is a rare yet life-threatening disease that is caused when the opportunistic pathogenic bacterium Staphylococcus aureus releases the toxic shock syndrome toxin 1 (TSST-1) superantigen, which triggers systemic inflammation. The main risk factor for mTSS is prolonged…

• Impact of Elexacaftor-Tezacaftor-Ivacaftor on fungal colonisation in children and adolescents with cystic fibrosis · 2026

  Résumé de la publication : Background CFTR modulators, such as elexacaftor/tezacaftor/ivacaftor (ETI), have markedly improved lung function in children with cystic fibrosis (cwCF). Their impact on fungal colonisation remains poorly investigated. Methods We conducted an ancillary prospective study within the real-world observational study MODUL-CF of cwCF naïve…