Unité de Bio-Informatique structurale

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Asymétrie de la membrane externe chez Veillonella parvula, un diderme Firmicute atypique · 2021

Publications HAL récentes repérées

• A connection between two ancient and essential cellular processes, iron-sulfur protein biogenesis and fatty acid synthesis, in Escherichia coli · 2026

  Résumé de la publication : ABSTRACT Iron-sulfur [Fe-S] clusters are ubiquitous cofactors of a wide array of structurally and functionally diverse proteins. Acyl carrier protein (ACP) is the universal factor required for fatty acid (FA) synthesis. In this study, in E. coli , we demonstrated that [Fe-S]…

• NMR, a tool for biology [meeting report] · 2026

  Résumé de la publication : Every 2 years the "NMR, a tool for biology" conference brings together renowned experts and emerging scientists to explore the application of nuclear magnetic resonance (NMR) in addressing fundamental biological questions. This international event in Paris showcases the latest methodological and application…

• An Optonanobody for Reversible Photoactivation of Recombinant and Native α7 Nicotinic Receptors · 2026

  Résumé de la publication : Photopharmacology, which enables the precise optical control of endogenous receptor activity, represents a powerful approach in neuroscience. However, photochromic diffusible ligands often exhibit limited subtype specificity, while alternative strategies for controlling specific receptor subtypes require genetic modification. Here, to achieve high subtype…

• Structural determinants of endopilus assembly, stability, and functional specificity in bacterial type II secretion · 2026

  Résumé de la publication : Gram-negative bacteria employ the type II secretion system (T2SS) to transport folded protein effectors via a periplasmic helical polymer called the endopilus, composed of one major and four minor pilin subunits. Endopili resemble type IV pili but feature a conserved calcium-binding site…

• The NMR Exchange Format (NEF): Specification and Applications · 2026

  Résumé de la publication : The NMR Exchange Format (NEF) is a community-driven standard for representing NMR experimental data in a consistent, interoperable, and machine-readable form. Built on the STAR syntax, NEF provides a structured framework for storing and exchanging chemical shifts, peak lists, various types of…