INSTITUT DE GENETIQUE ET DEVELOPPEMENT DE RENNES

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Décryptage de la spécialisation mitochondriale et de son contrôle temporel par les protéines du cycle cellulaire · 2026
• Régénération microvillaires chez les choanoflagellés et les cellules intestinales : principes de la régénération cellulaire à travers l'évolution · 2026
• Etude des rôles de l'ADP-ribosylation des histones lors de la réplication de l'ADN · 2026

Publications HAL récentes repérées

• ASMFNet: Anatomical symmetry-guided multi-modal fusion network for glioma segmentation in MRI · 2027

  Résumé de la publication : Glioma segmentation in multi-modal MRI is critical for clinical decision-making, but it remains challenging due to tumor heterogeneity and the complexity of multi-modal feature fusion. Although recent deep learning methods have achieved notable progress, they often struggle to effectively extract discriminative feature…

• Filamin a binds deleted in liver cancer 1 (DLC1) to promote its tumor suppressor activity and inhibit the SRF coactivator MRTF-A · 2026

  Résumé de la publication : Filamin A (FLNA) is an actin binding protein that organizes the cytoskeleton and controls many fundamental biological processes, such as cell migration and adhesion. The interaction between FLNA and the Myocardin-related transcription factor A (MRTF-A) promotes the activity of serum response factor…

• Molecularly targeted therapy and immunotherapy in leukemias · 2026

  Résumé de la publication : The advent of next-generation high-throughput sequencing and precision medicine has allowed the identification of recurrent genetic events of vital interest for leukemic cells and for the management of patients with leukemia, since it has a direct impact on prognosis and therapeutic stratification.…

• Phenotypic description of a large French series of individuals with Potocki-Lupski syndrome · 2026

  Résumé de la publication : Background: Potocki-Lupski syndrome (PTLS) is a rare genetic disorder, with an estimated prevalence of 1:25 000. Detection of a duplication at position 17p11.2 comprising the RAI1 gene establishes the diagnosis. Deletion of this same region is responsible for Smith-Magenis syndrome (SMS). Hitherto, the…

• Implementation and Optimization of a Random Illumination Microscope: towards Robustness for Microscopy Core Facility · 2026

  Résumé de la publication : Super-resolution microscopy has become an indispensable tool for investigating molecular architectures in their native cellular environment. However, most super-resolution techniques face limitations that prevent rapid, deep imaging of live samples. Random Illumination Microscopy (RIM), based on natural laser speckle illumination, is a…