INSTITUT COCHIN

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Modifications par O-N-Acétylglucosaminylation dans le COeur · 2026
• Impact de l'environement de la vessie sur les interactions phages-bactéries · 2026
• Chimie 3D innovante, mutagenèse exhaustive et modélisation intégrée pour anticiper et contrer l’évolution des carbapénémases de type Klebsiella pneumoniae carbapénèmase (KPC) · 2026

Publications HAL récentes repérées

• Predicting neonatal infection in PPROM with vaginal microbiology and metagenomics: a prospective cohort study · 2026

  Résumé de la publication : Objective Early-onset neonatal sepsis (EONS) due to ascending infection is a potentially preventable complication of preterm premature rupture of membranes (PPROM). Our objective was to determine whether the analysis of bacteria from vaginal swab samples is predictive of the risk of EONS…

• HIV persistence in tissues on dolutegravir-based therapy is not associated with resistance mutations to dolutegravir · 2026

  Résumé de la publication : Background : Relatively few studies have investigated HIV-1 persistence in tissues, especially in healthy people-living-with-HIV-1 (PLWH) on a successful antiretroviral regimen containing second generation integrase inhibitors. Methods : In the ANRS EP64 DOLUVOIR, we explore HIV-1 persistence in five accessible anatomical sites…

• Identification and functional validation of intracellular protein partners of phosphorothioate splice-switching oligonucleotides using AP-MS · 2026

  Résumé de la publication : Cellular uptake and intracellular distribution of phosphorothioate-modified antisense oligonucleotides (PS-ASOs) are mediated by protein interactions. While several PS-ASOs-binding proteins have been identified, mainly using gapmer designs with 2'-O-methoxyethyl (2'MOE) modifications, less is known about protein partners of splice-switching oligonucleotides (SSOs) with alternative…

• La production intestinale d’hepcidine réduit l’absorption du fer. Une nouvelle arme pour lutter contre les maladies de surcharge en fer ? · 2026

  Résumé de la publication : No abstract available

• Genomic diversification, adaptive convergence, and regulatory rewiring in aging Escherichia coli colonies · 2026

  Résumé de la publication : Background: Bacterial colonies are dynamic evolutionary microenvironments where spatial heterogeneity and nutrient gradients generate diverse ecological niches. Understanding how such structured environments drive genetic and functional diversification, including the emergence of clinically relevant traits such as antibiotic resistance, remains a major challenge.…