Médecine Cardiovasculaire Translationnelle (UR 3074)

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Publications HAL récentes repérées

• Synergistic Effects of SGLT2 Inhibitors and GLP-1R Agonists on Inflammation-Associated Oxidative Stress in Atrial Fibrillation · 2026

  Résumé de la publication : A trial fibrillation (AF) is the most common cardiac arrhythmia. It is a major cause of stroke and is strongly associated with heart failure (HF), particularly HF with preserved ejection fraction. Progressive electrical and structural remodeling of the atria underlie the concept…

• Synergistic SGLT2 and GLP-1R targeting alleviates systemic inflammation-induced and M1 monocyte-driven endothelial dysfunction in coronary artery disease · 2026

  Résumé de la publication : Background and objective Systemic residual inflammation plays a pivotal role in the pathophysiology of coronary artery disease (CAD). Cardiovascular protection by SGLT2 inhibitors (SGLT2i) and GLP-1 receptor agonists (GLP-1Ra) is associated with reduced inflammatory burden but underlying cellular mechanisms remain incompletely defined.…

• Rheumatic Heart Disease · 2026

  Résumé de la publication : Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young adults in endemic regions. No pharmacological intervention has been shown to modify…

• Clinical Impact of Guideline-Directed Medical Therapy in Patients with Left Ventricular Assist Device: An International Multicenter Study · 2026

  Résumé de la publication : Background: While guideline-directed medical therapy (GDMT) is recommended for left ventricular assist device (LVAD) recipients, real-world evidence supporting its clinical impact remains limited. This study evaluated the association between GDMT prescription and clinical outcomes in LVAD patients. Methods: This international retrospective multicenter…

• Artificial intelligence in cardiovascular care for internal medicine: from promising algorithms to useful clinical services · 2026

  Résumé de la publication : Artificial intelligence is expanding rapidly in cardiovascular medicine, but its value in internal medicine depends less on raw model performance than on whether it improves triage, risk targeting, and coordination of care within real-world workflows. Rather than cataloguing applications, this review focuses…