Unité Mort cellulaire et homéostasie des épithéliums

Domaines scientifiques déclarés au RNSR

Mots-clés des publications HAL repérées

Publications HAL récentes repérées

• Adhesion-controlled mechanics of the glial niche regulate neural stem cell proliferative potential · 2026

  Résumé de la publication : Stem cell proliferation drives tissue formation and homeostasis. Whether and how niche cell mechanics act in vivo to control this process remains unclear. Here, we identify a triad of cell adhesion molecules from the immunoglobulin superfamily, which physically link neural stem cells…

• Interfacial tension and growth both contribute to mechanical cell competition · 2025

  Résumé de la publication : Tissue plasticity and homeostasis rely on the interplay between cell behavior and mechanical inputs.1 Mechanical stress also contributes to the evolution of pathologies, notably by accelerating pretumoral cell expansion through mechanical cell competition (MCC).2,3,4,5 MCC is a conserved process in which one…

• Epithelial cell extrusion at a glance · 2025

  Résumé de la publication : The robustness and plasticity of epithelial tissues rely on the capacity of such tissues to eliminate cells without affecting their sealing. This is achieved by epithelial cell extrusiona well-orchestrated series of remodelling steps involving the eliminated cell and its neighbourswhich ensures the…

• Signaling-dependent refinement of cell fate choice during tissue remodeling in Drosophila pupal wings · 2025

  Résumé de la publication : How cell fate decisions and tissue remodeling are coordinated to establish precise and robust patterns is a fundamental question in developmental biology. Here, we investigate this interplay during the refinement of Drosophila wing veins. We show by live imaging that vein refinement…

• Epithelial cell death decision-making downstream of the effector caspases in vivo · 2025

  Résumé de la publication : Epithelial cell death via apoptosis is fundamental to the development of organ shape, regulation of cell numbers, and prevention of cancer. As such, an individual cell's decision to die within an epithelium can have wide-ranging consequences for the tissue and the organism.…