ULR 3610 - Laboratoire de Virologie - PATHOGENESE VIRALE

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Publications HAL récentes repérées

• Organic acid-based deep eutectic solvents (DESs) are potent antimicrobial agents against antibiotic-resistant bacteria and viruses · 2026

  Résumé de la publication : The escalating threat of antibiotic-resistant bacteria, biofilms and viral contamination in the healthcare and food industries threatens global health and requires the development of innovative antimicrobials. Deep eutectic solvents (DESs) have attracted attention as antimicrobial candidates, but there is little data on…

• A French national observatory of people with HIV initiating lenacapavir-based treatment after regulatory approval · 2026

  Résumé de la publication : There is limited data on lenacapavir (LEN) use, the newest capsid inhibitor, in observational settings. We describe population characteristics and pharmaco-virolog ical outcomes of people with HIV-1 (PWH) who initiated LEN-based treatment. We conducted a national retrospective observational study of PWH initiating…

• Respiratory syncytial virus (RSV) in older adults: from infection to outcomes – who gets sick, who gets hospitalized, who survives? · 2026

  Résumé de la publication : Respiratory syncytial virus (RSV) is a virus responsible for acute respiratory infections and is widely recognized as a major pathogen in the paediatric population. Thus, the burden of RSV in the adult population remains poorly understood, as epidemiological studies mainly rely on…

• Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France · 2026

  Résumé de la publication : Background: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants. Nirsevimab, a long-acting monoclonal antibody targeting a conserved epitope on the prefusion F protein (site Φ), has shown high efficacy in clinical trials and early real-world…

• Defective HIV-1 DNA pol sequences are not associated with HIV-1 DNA levels and drive most APOBEC-context drug resistance mutations · 2025

  Résumé de la publication : Introduction The specificity of HIV-1 DNA genotypic resistance tests (GRTs) is hampered by the detection of the APOBEC-context drug resistance mutations (AC DRMs), usually harboured by replication-incompetent proviruses. We sought factors associated with defective sequences in the HIV-1 pol region. In addition,…