PHYSIOPATHOLOGIE ET REGULATION DES TRANSPORTS IONIQUES

Domaines scientifiques déclarés au RNSR

Panels ERC déclarés au RNSR

Mots-clés des publications HAL repérées

Projets ANR

• Évaluation des effets thérapeutiques de la thérapie génique et des médicaments ciblant le cholestérol dans les organoïdes du muscle squelettique DMD · 2023

Publications HAL récentes repérées

• The Heart’s Hidden Neural Network: Interplay Between Intracardiac Ganglia, Fibrosis and Cardiac Remodeling · 2026

  Résumé de la publication : The heart’s performance relies on its contractile and rhythmic properties, which are modulated not only by extrinsic autonomic inputs but also by the intrinsic cardiac nervous system (ICNS), a distributed network of intracardiac ganglia and neurons that integrates local sensory, autonomic, and…

• Comparative evaluation of TRIDs : a strategy to improve treatments · 2026

  Résumé de la publication : No abstract available

• Quantification of intracellular mechanical fields in invasive cancer cells using digital volume correlation, confocal microscopy, and finite element method · 2026

  Résumé de la publication : Cell invasion process, which appears in the progression of tumours, such as glioblastoma, is highly dependent on cellular mobility. Cellular movement results from the interaction of chemical, biological and mechanical factors both inside and outside the invasive cancer cell. To identify and…

• Quantification of mechanical fields inside invasive cancer cells: Description of a new method using Digital Volume Correlation and Confocal Microscopy · 2026

  Résumé de la publication : Cell invasion process, which appears in the progression of tumors, such as glioblastoma, is highly dependent on cellular mobility. Cellular movement results from the interaction of chemical, biological and mechanical factors both inside and outside the invasive cancer cell. To identify and…

• The bone metastatic niche enhances GJA1-20k expression and mitochondrial remodeling in metastatic prostate cancer cells · 2026

  Résumé de la publication : Bone metastases are a major cause of morbidity in advanced prostate cancer (PCa), where tumor cells adapt to a hypoxic and osteoblast-rich microenvironment. Here, we investigated how endosteal niche conditions regulate GJA1-20k expression and mitochondrial dynamics in metastatic PCa cells. We demonstrate…